Tuberculin skin testing: Spectrum of adverse reactions

Tuberculin Skin Testing in Children

In 1996, the American Academy of Pediatrics (AAP) recommended targeted tuberculin skin testing (TST) of children while discouraging routine TST of children without risk factors for tuberculosis (TB). Recent studies have provided evidence in support of the targeted TST and recommendations that favor risk assessment over universal screening with TST. While evidence for targeted TB testing exists ...

Serious allergic reactions following tuberculin skin tests.

Erlotinib-induced Adverse Skin Reactions

Erlotinib is low molecular-weight quinazolin derivatives which selectively inhibit the epidermal growth factor receptor (EGF-R) tyrosine kinase activity of the intracellular domain, block autophosphorylation and the subsequent signaling cascades. EGF-R is expressed on basal keratinocytes, sebocytes, the outer root sheath of hairs, and endothelial cells in the skin, and plays important roles in ...

The Booster Phenomenon of Tuberculin Skin Testing in Patients Receiving Hemo-dialysis

Background: The risk of developing tuberculosis is high among chronic hemodialysis patients. The tuberculin skin test (TST) has been in use for diagnosing latent TB, but few data are available on TST in hemodialysis patients. Objective: This study was done to identify the TST reactivity and frequency of booster effect in serial TST among hemodialysis patients. Methods: A total of 100 patients i...

Prevalence of tuberculin skin test reactions among prison workers.

OBJECTIVE To determine the prevalence of positive tuberculin skin test (TST) reactions (10 mm or greater) among full-time employees of a provincial prison for women in Montreal. METHODS Participants underwent tuberculin skin testing and completed a self-administered questionnaire. RESULTS Among 129 employees identified, 118 (91%) underwent tuberculin testing. Among 102 born in Quebec who co...